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Each spot was spiked with 8L of a 1 ng/mL solution of MRFA (tetrapeptide used as internal standard) and dried at room temperature for 30 minutes

The inclusion criteria was as follows: Age 18-45 years, regardless of sex and economic and social background, Caucasian race, the presence of heart rhythm disturbances in non-structural heart disease, confirmed clinically and investigatedby electrocardiogram, Holter-ECG device, echocardiography and laboratory findings (presence/absence of dyslipidemia)

Unlike EMPA 1, the EMPA 3 group showed a significant increase in relative mBDNF/proBDNF expression in relation to PTZ-expressed levels, suggesting its potentiated neuroprotective effects when compared to the EMPA 1 group

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