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Excessive fat storage causes stress reactions within the fat cells, leading to inflammation
GLP-1 receptor agonists can promote natriuresis (increased sodium excretion in urine), but clinically meaningful electrolyte disturbances are uncommon unless dehydration or reduced intake occurs
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A corresponding increase in the expression of oxidant generators, such as NOX1 and inducible nitric oxide synthase, also contributed to inflammation and apoptosis in this brain injury model [113]
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