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Collectively, our data suggest that injected fibroblasts can induce NP cells to adopt a fibroblastic phenotype via the TGF/Smad signaling pathway, leading to reparative fibrosis of the IVD, which helps to suppress further degeneration of the intervertebral disc

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The practical takeaway is not supplement and relax, but avoid abrupt restriction. If your cat is overweight, the most elegant plan is slow and steady: measured meals, high-quality protein, and a routine that keeps appetite and mood stable