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Disruption of the MTOC results in defects in spindle assembly and subsequent arrest in oocyte development ( 2.4 Oxidative stress leads to dysfunction of the spindle assembly checkpoint The spindle assembly checkpoint (SAC) functions as a pivotal regulatory mechanism within the cell cycle ( 2.5 Strategies to mitigate oxidative stress for the prevention of oocyte deterioration As women age, reproductive senescence is linked to increased oxidative stress within the ovaries
It is often referred to as the body's "master antioxidant" due to its vital role in protecting cells from oxidative stress, a condition that can lead to chronic diseases and accelerate aging
Eligibility criteria Inclusion criteria were: RCTs compared oral ALC to placebo, irrespec tive of medication, blinding, publication status or language published as full-length articles in peer-reviewed journals
Several nutrients are commonly combined with glutathione
