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Do not adjust tirzepatide dosing based on this temporary effect

In these cases, vitamin D supplementation in the form of a shot may be recommended

Biomed Pharmacother 189:118325

Semaglutide-treated rats show downregulation of many type IV and type VI collagens and laminin genes that compose the basement membrane, as well as the type I, type III, and type V collagens and fibrillins that compose the interstitial matrix ( Figure 4B )