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Pregnancy and breastfeeding : Semaglutide should not be used during pregnancy and should be discontinued at least two months before a planned pregnancy

Schematic illustrating the process of xenobiotic metabolism, which encompasses three phases I, II, III (Adopted from [137]) as well as xenobiotic induced oxidative stress and molecular damage

Other mechanisms presumably involve active tubular secretion via renal transporters (Organic Anion Transporter-3 (OAT3) or P-glycoprotein (P-gp))

While this leads to more spontaneous pregnancies, studies havent shown the same increase in success for those undergoing in vitro fertilization (IVF)