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Tirzepatide: The Stronger Option Tirzepatide: The Stronger Option Tirzepatide (Zepbound for weight loss, Mounjaro for diabetes) hits two receptor pathways, GLP-1 and GIP instead of one

doi: 10.1016/j.jddst.2019.05.041 Summary Keywords psoriasis, thymoquinone, topical therapy, nano-thymoquinone, nano-formulation Citation Modarresi Chahardehi A, Ojaghi HR, Motedayyen H and Arefnezhad R (2024) Nano-based formulations of thymoquinone are new approaches for psoriasis treatment: a literature review

Cell pellets (~2030 l of packed cell pellet) were re-suspended in 1 ml buffer containing 20 mM HEPES (pH = 7.5), 10 mM KCl, 250 mM sucrose, 5 mM MgCl 2 , 1 mM EGTA, 1x phosphatase inhibitor cocktail (Sigma, P0044) and 1x protease inhibitor cocktail (Sigma, P8340), and lysed by addition of digitonin (Sigma, D141), 200 g/ml final concentration at 4 C for 10 min

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