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At subacute timepoints, these PCs and PEs (particularly those containing polyunsaturated fatty acids) as well as SMs and LPC 20:2 are downregulated, while diaglycerols and free fatty acids/polyunsaturated fatty acids are increased in serum of rats with TBI [87]

One potential issue associated with high doses of folic acid is that it has a masking effect on the diagnosis of pernicious anaemia due to vitamin B 12 deficiency, and may even precipitate or exacerbate neuropathy in vitamin B12-deficient individuals

The mean values are shown on Table 8