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Insurance companies and PBMs are now under intense scrutiny for their role in the pricing chain, with new federal transparency laws taking effect in 2026

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The three protocols most relevant for Medicare seniors making an entry-tier decision are: Microdose GLP-1 Protocol at $129/mo flat compounded GLP-1 in four delivery variants (capsule, troche, lozenge, sublingual), provider-selected dosing, the lowest entry tier in the PlexusDx lineup and a sensible starting point for seniors who want a needle-free option or a slower titration baseline before considering injection therapy

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