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Shukitt-Hale B, McEwen JJ, Szprengiel A, Joseph JA (2004) Effect of age on the radial arm water maze-a test of spatial learning and memory

This reduction in glutathione levels is associated with increased susceptibility to oxidative stress and age-related health issues

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The combination of NADPH and Mito-apocynin, a mitochondria-specific NADPH oxidase (NOX) inhibitor, effectively reversed KA-induced neuronal damage and the down-regulation of TP53-induced glycolysis and apoptosis regulator and NOX4 [122]