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Long-term oral studies of acetylcysteine alone in rats (12 months of treatment followed by 6 months of observation) at doses up to 1,000 mg/kg/day (5.2 times the human mucolytic dose) provided no evidence of oncogenic activity

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Despite recognition of the severe medical and socioeconomic burden of obesity, the weight-loss effects of pre-existing AOMs are insufficient to overcome obesity-associated complications

We confirmed exopher suppression in ifd-1() and ifd-2() using alternative reporter cargo encoded by uIs31 [P mec-17 GFP] (Supplementary Fig