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Subsequently, combined analysis of these genes with the 1551 upregulated DEGs identified in our study led to the identification of 12 candidate ROS-associated upregulated DEGs in COAD, including NDUFA13, PRDX2, TSPO, ROMO1, NDUFS3, EIF6, SOD1, CYBA, DUOXA2, NOXO1, GLS2, and NOS2