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41 The controversial JUPITER trial, which examined prevention of CHD by statin drugs in persons with very low LDL cholesterol (but elevated highly-sensitive C-reactive protein [hs-CRP]) supported the conclusion that non-LDL cholesterol risk factors (such as inflammation) represent enough risk for CHD to warrant treatment, even if lipids are within low-risk ranges

Said to be the first meta-analysis to investigate the effect of L-carnitine supplementation on the biomarkers of metabolic syndromes, the analysis examined nine RCTs that were published before February this year