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Its clear that the nuances of Pernicious Anemia and B12 treatment are a significant concern, and I appreciate you providing additional context and scientific information
[DOI] [PMC free article] [PubMed] [Google Scholar] 7
Based on patient reports and clinical patterns, the answer for many patients appears to be yes, particularly those who've had poor experiences at less medicalized facilities or who have complex health profiles requiring customization
sCT when bound to AMYRs induce a CT-like receptor conformation 15 , while P32Y substitutions of CT analogues are also detrimental to affinity and potency at AMYRs 18,19
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