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On the other hand, if the EUS results are negative, these individuals will be monitored every 36 months up to 36 months for clinical signs and symptoms for PDAC.( Figure 5 ) By using a tiered approach to identify PDAC-associated diabetes in the NOD risk group, we would limit costly invasive tools for the highest risk individuals, prevent cumulative radiation exposure by CT (112), while acknowledging that the greatest proportion of NOD individuals will have T2D

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Mechanism Selective NNMT inhibition, proposed to preserve intracellular NAD+/SAM and reduce fat-cell lipogenesis demonstrated in mice, not humans