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Comparison of clinical outcomes and adverse events associated with glucose-lowering drugs in patients with type 2 diabetes: a meta-analysis

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The growing literature and postmarketing safety signals point to common gastrointestinal side effects such as nausea, vomiting and diarrhea, while observational studies have raised concerns about pancreatitis, gallbladder disease and other complications

GLP-1 therapy is particularly considered in patients with a BMI 35 kg/m or those who would benefit from weight loss