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Modulation of PKM2 inhibits follicular helper T cell differentiation and ameliorates inflammation in lupus-prone mice
This three-pronged approach has demonstrated significant anticancer efficacy in xenograft models [147]
This form is highly regarded for its improved bioavailability and effectiveness in supporting detoxification, immune health, and antioxidant defenses
A broader investigation into alternative regulatory modalities, such as ligand-dependent cytoplasmic sequestration or post-translational modifications, could provide new insights into nuclear receptor biology and help address the challenges of deorphanization
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