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Su funcin es perifrica (msculo, corazn, hgado) y no involucra al sistema nervioso central porque no cruza la barrera hematoenceflica (BHE) en cantidades fisiolgicamente relevantes cuando se ingiere como suplemento

The results showed that tirzepatide was well-tolerated, with most participants experiencing mild to moderate adverse events such as nasopharyngitis, nausea, constipation, diarrhea, and decreased appetite

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The right response to prevent lean mass loss is nutrition and resistance training support, not assuming that a lower drug dose is inherently muscle-sparing