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In rodent models of retinitis pigmentosa an inherited condition where light-sensing cells in the retina gradually die, leading to progressive vision loss TUDCA reduced retinal cell death and preserved photoreceptor structure and function.34 35 Other animal studies suggest benefits in models of light-induced retinal damage and diabetic retinopathy, again showing reduced apoptosis of retinal cells.25 36 TUDCA appears to protect retinal cells in several preclinical models

Wang X, Sirianni A, Pei Z, Cormier K, Smith K, Jiang J, Zhou S, Wang H, Zhao R, Yano H, Kim JE, Li W, Kristal BS, Ferrante RJ, Friedlander RM (2011) The melatonin MT1 receptor axis modulates mutant Huntingtin-mediated toxicity

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