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Mobile phase A was 10 mM ammonium acetate (pH 10, adjusted with ammonium hydroxide) in water and mobile phase B was prepared with 10% A / 90% ACN

In some embodiments, a high viscosity otic formulation or device described herein provides an apparent viscosity of from about 250,000 cP to about 500,000 cP

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Voicehovska, J