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How Insulin Resistance Affects Your Body When your body becomes resistant to insulin, several key things happen: Sugar stays in your bloodstream instead of entering your cells, which can cause energy crashes and cravings

If you notice weakened appetite suppression, slower weight loss trajectory, or reduced satiety compared to earlier doses despite consistent technique, your medication's effectiveness may have declined from storage problems

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Since your body cant make its vitamin B12, you need to get it from external sources