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That delay can increase the risk of regurgitation and aspiration during induction of general anesthesia

The most critical period for damage appears to be during the first trimester, resulting in birth defects affecting the cardiovascular system, central nervous system, facial area, and thymus (an organ involved in immune cell production)

Preserves lean muscle mass, preventing muscle loss during weight reduction

For global health applications, room-temperature stability is particularly important: it enables distribution in tropical climates without the cold-chain infrastructure that limits access to injectable biologics in much of the developing world