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Additionally, IBS patients with constipation have been found to have lower natural GLP-1 levels , and lower GLP-1 correlated with more pain, suggesting a deficiency of GLP-1 signaling might be related to IBS symptoms

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Regulatory status

For example, a study recently found that amino acids can modify protein targets on the lysine residue, namely aminoacylation, which transduces amino acid signals to regulate cellular functions (He et al., 2018)