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This process contributes to improved tissue functional status, analogously to the biological principle where the removal of dysfunctional structures allows for more efficient resource utilization by healthy cells

This histopathological hallmark enables the observation of lesion rims by MRI and correlates with high levels of serum neurofilament light chain, therefore with axonal injury, and with disease severity (141, 142)

During the consultation, patients should expect a thorough discussion of realistic expectations, as weight loss from medications in the post-bariatric setting may differ from results seen in medication-naive patients