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In conclusion, Metanx, at the dose currently employed in clinical practice, alleviates sensory large and small fiber DPN and induces small sensory nerve fiber regeneration, by mechanisms that are likely to involve inhibition of oxidative-nitrosative stress

Marso SP et al

symptom management and orthotic support AFO for foot drop (L-code orthoses), custom footwear, surgery for foot deformity (pes cavus correction) Genetic counseling: document gene mutation identified (PMP22 duplication CMT1A, GJB1 CMTX, MFN2 CMT2A) Avoid neurotoxic drugs (vincristine, colchicine) document CMT diagnosis prominently in medication reconciliation Patient Education / Summary Patient education documentation supports coding specificity and demonstrates active management of neuropathy complications

Clinical data on visceral fat reduction (tesamorelin) was measured at 26 weeks