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2012) Exenatide has 53% homology with GLP-1

So to answer your question directly, there are some people who probably don't have that thrifty gene, but just the fact of how their lifestyle is they're not physically active, they're eating a lot of highly processed food and so forth they're gaining weight, but that can change quickly depending upon change in their behavior and in their environment

Regular check-ins with your provider will track your progress and allow for dosage or delivery method adjustments to maximize effectiveness

The challenge is distinguishing semaglutide's direct neurological effects from indirect benefits of weight loss and improved metabolic health