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Most immune cells, including CD4 + T cells, B cells, and NK cells, upregulate genes related to the cholinergic system synthesis in response to inflammatory cues, which is pivotal for the maintenance of immunological homeostasis ( 2.2.1 B cells B cell maturation and differentiation into plasma cells require robust phospholipid synthesis and remodeling to sustain multiple rounds of proliferation, clonal expansion, and antibody production ( Figure 3 )

Genome-level expression profiles in pediatric septic shock indicate a role for altered zinc homeostasis in poor outcome

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Point mutations in the proline-rich region of p22phox are dominant inhibitors of Nox1- and Nox2-dependent reactive oxygen generation