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In this review, we first summarize the principles and fabrication strategies underlying OoC technology, then trace their evolution toward autologous systems capable of modeling autoimmune diseases and assessing drug efficacy and safety in a translationally relevant manner

This will vary from person to person due to age, lifestyle, dietary requirements and other health considerations

401 These findings suggest that Schwann cells under impaired metabolic conditions release pathologic EVs that promote nerve degeneration and DPN, whereas homeostatic EVs may facilitate nerve repair

4.2 Drug-induced liver injury (DILI) Drug-induced liver injury (DILI) refers to liver damage caused by exposure to medications