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Description

Exenatide once-weekly clinical development: safety and efficacy across a range of background therapies

The p7, a 63 aa small polypeptide, contains two transmembrane -helix domains connected by a cytoplasmic loop

Together, they create a more natural stimulation of growth hormone over time

1990 Pivotal study in older men: six months of HGH (0.03 mg/kg 3 weekly) significantly increased lean body mass and decreased adipose mass compared to placebo Gtherstrm et al., J