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(3) Subjects should meet any three of the following five criteria for metabolic syndrome as described by Grundy et al

Biermann has heard from many GLP-1 users who want to stop the medication and is studying whether gradually spacing out doses such as moving from weekly injections to every other week can help maintain weight loss and other health benefits

Any switch should be clinician-directed

Retatrutide may interest people who: are curious about next-generation metabolic therapies, want a broader metabolic approach, or are interested in therapies that may influence both appetite and energy expenditure