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GLP-1 receptors are expressed in the hypothalamus, the brainstem, and other central nervous system regions that regulate autonomic tone

Jimmy Johannes, MD, pulmonologist and critical care medicine specialist at MemorialCare Long Beach Medical Center, spoke with Medical News Today about the study

The scientific studies of these experimental drugs were never large enough or long enough to establish a clear safety profile, so all we are left with are vague reassurances from tiny studies and testimonials from YouTubers and TikTokers

While this mechanism is exactly what helps you feel full longer and prevents blood sugar spikes, it can also lead to constipation for two primary reasons: Not enough fluid intake: When you feel full, you tend to drink less water