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Prioritize protein (0.7 to 1.0 grams per pound of target body weight), eat frequent small meals rather than large infrequent ones, limit high-fat foods during dose increases to reduce nausea, stay hydrated, and avoid alcohol (which worsens both GI side effects and calorie intake)

Some patients must continue to take supplements or receive injections for life depending on the reason for the deficiency

In terms of selecting the formulation delivery device, in a human study with a whole-virus influenza liquid vaccine without adjuvant, the immune response was better when using the breath-powered Bi-Directional OptiNose device and nasal drops in the delivery, rather than traditional nasal spray and an oral spray [22]

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