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Exposure to phentermine or GLP-1 medications in the first trimester yielded similar results to exposure in the 90 days prior to pregnancy, as shown in Figure 3

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Treatment response : As per NICE guidance, assess response after 6 months and continue only if adequate benefit is demonstrated (HbA1c reduction of at least 11 mmol/mol [1%] and/or 3% weight loss from initial body weight)