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The treatment with the nanoreactors demonstrated to nearly fully eradicate an aggressive osteosarcoma inside the animal model

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Chemotherapy is the mainstay of control against human liver fluke infections, which is recommended by WHO and adopted in major endemic countries (Table 4) (256)

Despite the substantial conformational dynamics when bound to AMY 3 R, Cagri maintains the bypass conformation across the motions, likely arising from the consistent TMD and linker interactions between RAMP3 and CTR that enable robust engagement of residues within the Cagri bypass motif