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How They Differ The differences are entirely in dosage, FDA approval, and marketing : Ozempic (Diabetes Medication) FDA-Approved Use: Treatment of Type 2 Diabetes Mellitus Reducing cardiovascular risk in diabetic patients Dosing Schedule: Starting dose: 0.25 mg weekly (first 4 weeks) Maintenance dose: 0.5 mg or 1.0 mg weekly Maximum dose: 2.0 mg weekly Intended Primary Effect: Blood sugar control A1C reduction Weight Loss Status: Acknowledged as a side effect Not the primary indication Insurance may not cover for weight loss alone Off-Label Use Reality: Many doctors prescribed Ozempic specifically for weight loss before Wegovy became available

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This is particularly important with tirzepatide, which can reduce oral contraceptive exposure during initiation and dose escalation, potentially requiring backup contraception