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Desde sua descoberta nos anos 1990 pela equipe do professor Predrag Sikiri na Universidade de Zagreb, este pentadecapeptdeo tem despertado um interesse crescente por parte da comunidade cientfica e dos profissionais de sade

In the case of low back pain we see this pattern most commonly present, as illustrated in Image 1 3 : Tight Muscles Rectus femoris muscle of the quads Iliopsoas muscle in the back and hip Lower Back muscles Weak Muscles Core Muscles transverse abdominus and obliques Gluteal muscles gluteus medius and gluteus maximus These muscle imbalances cause the pelvis to tilt forward, and put pressure on the vertebrae and discs in the lumbar spine