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When asked about the impact of Covid-19, 58% said the pandemic had affected their care, including treatments being stopped or cancelled

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Given that acetyl-l-carnitine has a neuroprotective action shown in an animal model of ALS [85], it was hypothesised that treatment with acetyl-l-carnitine could help patients with ALS

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Commonly, ROS play a prominent causal role in LMP that H 2 O 2 -driven luminal production of hydroxyl radicals by Fenton reaction leads to the destabilization of lysosome membrane upon massive peroxidation of membrane lipids [179, 180]

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