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Conversely, mice with constitutive and postnatal ablation of Htr2c in POMC neurons are hyperphagic but retain functional energy expenditure responses [69], whereas Glp1r deletion in POMC neurons has only subtle effects on weight gain in high-fat diet [131]

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The Italian-style restaurant chain also wanted to appeal to patrons pursuing healthier diets or more affordable meals, said Rick Cardenas, the president and CEO of Olive Gardens parent company, Darden Restaurants