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African ancestry GWAS identifies new loci not previously identified with European GWAS data During our investigation into the genetic factors contributing to POAG within the African ancestry group (1,339 POAG cases, 69,491 controls), we uncovered novel associations that highlight the intricate genetic complexity and remarkable diversity present in POAG genes in different populations

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Recent findings indicate that 7nAChR activation may cause pathological angiogenesis in diabetic retinopathy by boosting VEGF expression [310, 311]