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In fact, it had been documented more than ten years earlier that when ascorbic acid and glutathione are together in the presence of the hexoxidase [ascorbate oxidase] described by Szent-Gyorgyi the glutathione wholly protects the vitamin from oxidation, whilst it is itself oxidized at a rate which, with the same concentration of enzyme, is exactly the same as the rate with which ascorbic acid is oxidized when alone. (Hopkins and Morgan 1938)
In addition to the absolute number, the type of bacteria present in the small intestine can also impact the signs and symptoms a person may experience
Dall'Oglio F, Puviani M, Milani M, Micali G
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