According to the Medicines and Healthcare products Regulatory Agency (MHRA) and National Institute for Health and Care Excellence (NICE) guidance, it may be prescribed as: Monotherapy when diet and exercise alone do not provide adequate glycaemic control and when metformin is considered inappropriate due to intolerance or contraindications Add-on therapy in combination with other glucose-lowering medications, including metformin, sulfonylureas, sodium-glucose co-transporter-2 (SGLT2) inhibitors, or insulin, when existing treatment does not achieve target HbA1c levels NICE Technology Appraisal 653 (TA653) recommends oral semaglutide as an option for treating type 2 diabetes in adults when a GLP-1 receptor agonist would otherwise be appropriate according to NICE guideline NG28
These ingredients, sourced from natural sources like fruits, vegetables, and herbs, are rich in compounds such as vitamins, minerals, and phytochemicals that possess potent antioxidant properties
Napolitano A, Miller S, Murgatroyd PR, et al
Additionally, some patients may experience changes in their dietary habits when starting these medications, such as reduced appetite or altered food choices, which can further contribute to digestive issues