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The most common patient complaints are minor: soreness at injection site, a transient headache, or mild diarrhea

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The ATP-binding cassette (ABC) transporters, including P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP), expressed on the luminal endothelial plasma membrane, are pivotal in CNS pharmaco-resistance [24, 30,31,32]

Likewise, preserving density for the next five years may be just as important as achieving visible thickening over the next six months