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FIGURE 2 The ADME properties of the main ingredients of Fibraurea recisa Pierre The ADME-related properties of the main ingredients of FRP were evaluated in depth using the online tool ADMETlab 2.0, and all of them conformed to Lipinskis five laws ( n 1), including the topological acute surface area (TPSA) and solubility (LogS) indexes

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Based on visual inspection during the experimental period (3538 weeks old), MC4R KO mice appeared to have a longer body length compared to wild-type controls, which is consistent with the findings reported by Braun et al