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When combined with exercise and a healthy diet, they have been life-changing for many people with obesity and/or type 2 diabetes

Biochim Biophys Acta 995:97101 Li C, Chen P, Palladino A, Narayan S, Russell LK, Sayed S, Xiong G, Chen J, Stokes D, Butt YM, Jones PM, Collins HW, Cohen NA, Cohen AS, Nissim I, Smith TJ, Strauss AW, Matschinsky FM, Bennett MJ, Stanley CA (2010) Mechanism of hyperinsulinism in short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency involves activation of glutamate dehydrogenase

Anti-obesity medications can be extremely helpful and effective when combined with behavior and lifestyle change

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