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You should contact your GP if you experience: Persistent fatigue or general malaise Discomfort or a sensation of fullness in the right upper abdomen Unexplained weight loss Seek same-day or urgent medical attention if you develop: Jaundice (yellowing of skin or eyes), especially with fever or feeling systemically unwell Dark urine or pale stools Easy bruising or bleeding, or vomiting blood Swelling of the abdomen or legs that is rapidly worsening Confusion or difficulty concentrating (potential signs of hepatic encephalopathy) Severe abdominal pain with fever Risk factor assessment is equally important

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Iversen, P

Telomere attrition is linked not just to aging, but to cardiovascular disease, immune decline, type 2 diabetes, and neurodegeneration [28,29, 30]