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Liraglutide (Victoza) was approved in 2010, followed by Saxenda (for weight loss) in 2014.33 Semaglutide (Ozempic) was approved in 2017, Wegovy (for weight loss) in 2021, and Rybelsus (oral) shortly thereafter

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Melanotan II (MT-II) is a synthetic analog of the naturally occurring melanocyte-stimulating hormone (-MSH) that was originally developed for its tanning properties