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Partial reduction reactions occur even under physiologic conditions, causing release of superoxide radical (O 2 ) and hydrogen peroxide.[] NATURAL SOURCES OF GLUTATHIONE Glutathione is available naturally in fresh leafy vegetables, broccoli, walnuts, chestnuts, oranges, whey protein, tomatoes, fresh fruits, avocados, asparagus, meat, and poultry.[] PHARMACEUTICAL FORMULATIONS OF GLUTATHIONE Glutathione is available as oral preparations (pills, sublingual tablets, solutions, syrups, and sprays) and parenteral forms (IV preparations)

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MR acetaminophen is available in Australia and New Zealand and contains 665 mg paracetamol, 31% immediate release, and 69% slow release

They also reported that these patients had higher levels of interleukin 1 (IL-1), IL-6, and TNF- , suggesting an inflammatory state and oxidative stress in migraine patients (112)