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FIGURE 4 At the molecular level, AD skin lesions exhibit significant downregulation of structural proteins such as filaggrin and claudin-1 (Melnik, 2015

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Similar content being viewed by others Introduction Dimethyl sulfoxide (DMSO) is the most commonly used nonaqueous solvent and is classified as class 3 (nontoxic) by the United States Food and Drug Administration (FDA) and the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) 1,2

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