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Deiodinases (DIOs) regulate thyroid hormone metabolism by catalyzing the conversion of thyroid hormones from precursor thyroxine (T 4 ) to biologically active triiodothyronine (T 3 ) or inactive reverse T 3 (rT 3 ) 54

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In vitro studies have shown that OGP can regulate osteoprogenitor cell proliferation, differentiation, alkaline phosphatase activity, osteocalcin secretion, collagen and matrix mineralization [8587, 92]

But admittedly it can be hard to tell for those who always have some degree of breakouts