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These factors coordinate transformation of precursor cells into mature contractile fibers

It is found in every cell of the body, particularly in the liver, where it helps neutralize free radicals, detoxify harmful substances, and l I support immune function

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Mitochondrial dysfunction is characterized by various degrees of ultrastructural mitochondrial damage, abnormal morphologic changes, increased permeability of the outer and inner membranes, impaired mitochondrial -oxidation, respiratory chain activity reduction, ROS overproduction, ATP depletion, and oxidative stress-mediated deletions of mtDNA inducing apoptosis (Ramanathan et al